Metabolism and Functions of Bioactive Ether Lipids in the Brain (PDF)

by
Akhlaq A. Farooqui, Tahira Farooqui, Lloyd A. HorrocksAkhlaq A. Farooqui, Tahira Farooqui, Lloyd A. Horrocks

Information on bioactive ether lipids and their involvement in neurological disorders is currently scattered throughout the literature in the form of original papers and reviews. Metabolism and Function of Bioactive Ether Lipids in the Brain provides readers with a comprehensive description of metabolism of bioactive ether lipids in the brain, activities of enzymes involved in their metabolism, and their involvement in neurological disorders. This book will be particularly useful to neuroscience graduate students, academics, and researchers. Clinicians will find this book useful for understanding molecular aspects of neurodegeneration in acute neural trauma and neurodegenerative diseases that are mediated by plamalogen-selective phospholipases A2 and PAF acetyl hydrolases. This monograph is the first to provide a comprehensive description of not only metabolism and role of plasmalogen and platelet activating factor in brain tissue but also the involvement of these lipids with abnormal signal transduction processes in neurological disorders. Key Features
• Provides the neuroscience community with extensive description of ether lipids-derived lipid mediators their roles and association with neurological disorders
• Particular attention given to the description of keys enzymes associated with the generation of ether lipid-derived lipid mediators
• Illustrated with chemical structures and line diagrams of signal transduction pathways
• Discusses the future direction of research on ether lipid metabolism

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