High-Resolution NMR Techniques in Organic Chemistry, Third Edition

High-Resolution NMR Techniques in Organic Chemistry, Third Edition describes the most important NMR spectroscopy techniques for the structure elucidation of organic molecules and the investigation of their behaviour in solution. Appropriate for advanced undergraduate and graduate students, research chemists and NMR facility managers, this thorough revision covers practical aspects of NMR techniques and instrumentation, data collection, and spectrum interpretation. It describes all major classes of one- and two-dimensional NMR experiments including homonuclear and heteronuclear correlations, the nuclear Overhauser effect, diffusion measurements, and techniques for studying protein-ligand interactions. A trusted authority on this critical expertise, High-Resolution NMR Techniques in Organic Chemistry, Third Edition is an essential resource for every chemist and NMR spectroscopist.

• Uniquely covers NMR instrumentation, pulse techniques, experimental methods, and spectrum analysis
• Focuses on methods and examples vital for the practicing chemist and research student
• Uses accessible figures to present and explain techniques, limiting complex mathematical descriptions

New to this Edition

• New section describing dynamic exchange processes and their analysis
• New sections on modern developments including residual dipolar couplings, pure-shift NMR, multiple receivers, fast methods, and hyperpolarization
• New chapter on using NMR methods to study protein-ligand binding processes; applicable to life science and medicinal chemistry research in industry and academia
• New chapter on the application of 1D and 2D methods via a worked example; readers can view the spectra, follow the interpretation, and collect their own data for comparison and practice