Masters of Pathology Series

A wide-ranging review of pathology and laboratory science as it pertains to the female genital tract. Earn Lifelong Learning and SAM credits.

Recognizing Gynecologic Tumors

Gynecologic Pathology focuses on tumors of the gynecologic tract: how to distinguish between them, how to recognize tumors that secondarily involve the gynecologic tract and how to recognize benign mimics of malignancy. Lectures are organized by anatomical location (i.e., uterus, cervix, vulva, ovary, fallopian tube) and histotype. Wherever relevant, speakers include a description of precursor lesions, interventions for early detection and a summary of molecular genetics as it applies to diagnosis, prognosis, therapeutic prediction, and screening for hereditary cancer syndromes.

Learning Objectives

At the conclusion of this CME activity, the participant will be able to:

• Recognize differentiated vulvar intraepithelial neoplasia
• Diagnose cervical carcinoma
• Apply ancillary tests to refine diagnosis and prognosis
• Differentiate between type of endometrial carcinoma
• Diagnose endometrial carcinoma
• Apply universal testing to detect Lynch syndrome patients
• Recognize risk reducing salpingo-oophorectomy specimens and precursor lesions
• Interpret problematic endometrial biopsies
• Distinguish between endometrioid and serous carcinomas of the ovary
• Diagnose clear cell carcinomas of the gynecologic tract
• Use molecular pathology for precision endometrial carcinoma diagnosis
• Apply diagnostic criteria, ancillary testing, triage for inherited family cancer syndromes for cancers, pre-cancers and mimics of cancer

Intended Audience

This educational activity is intended for training and practicing pathologists and gynecologists.

• Cervicovaginal Carcinomas and Precursors – Robert A. Soslow, MD

• Endocervical Adenocarcinomas and Precursors – Robert A. Soslow, MD

• Vulvar Tumors, Precursors and Non-Neoplastic Mimics – Robert A. Soslow, MD

• Low-grade Serous Neoplasia of the Ovary (Borderline Tumors and Low-Grade Serous Carcinoma) – Robert A. Soslow, MD

• High-Grade Serous Carcinomas of the Female Adnexa, the BRCA Story and Evaluation of Risk-Reducing – Salpingo-oophorectomy Specimens – Robert A. Soslow, MD

• Uterine Smooth Muscle Tumors – Robert A. Soslow, MD

• Uterine Mesenchymal Tumors other than Smooth Muscle Tumors – Robert A. Soslow, MD

• Mixed Epithelial-Stromal Tumors of Uterus and Adnexa – Robert A. Soslow, MD

• Endometrial Biopsy Interpretation – Robert A. Soslow, MD

• Endometrial Carcinoma: Mimics and Subtypes – Robert A. Soslow, MD

• Endometrial Carcinoma: Staging, Grading and Lynch Syndrome Testing – Robert A. Soslow, MD

• High Grade Endometrial Carcinoma: Morphologic/Genetic Correlations – Robert A. Soslow, MD

• Gestational Trophoblastic Disease – Sarah Chiang, MD

• Ovarian Sex Cord Stromal – Esther Oliva, MD

• Germ Cell Tumors – Esther Oliva, MD

• Ovarian Endometrioid Tumors – Robert A. Soslow, MD

• Clear Cell Carcinomas of Endometrium and Ovary – Robert A. Soslow, MD