Johns Hopkins Clinical Update

Improve clinical performance with this authoritative review of the latest concepts and techniques in the interpretation of gastrointestinal and liver specimens.

Improve Your Ability to Interpret Gastrointestinal and Liver Specimens

This recording of Johns Hopkins’ 17th Annual Current Topics in Gastrointestinal and Liver Pathology event delivers a practical overview for pathologists who encounter gastrointestinal and liver specimens in daily practice. Interpretation of biopsies of the upper GI tract mucosa and the liver will be addressed, as well as recent advances in pancreatic and biliary pathology. Participants should come away with a better understanding of interpretation of mucosal biopsies, liver biopsies, pancreatic/biliary disorders, and the application of modern techniques to gastrointestinal disorders.

• Esophagitis is a Pain in the Neck – Joel Greenson, MD

• Common Issues and Challenging Cases from the GI Consultation Service – Lysandra Voltaggio, MD

• Genomic Test Interpretation for the Gastrointestinal Surgical Pathologist – Jason Park, MD, PhD

• Iatrogenic Findings in the GI Tract: From Curious to Critical – Dora Lam-Himlin, MD

• Molecular Pathology of Colorectal Cancer – Jason Park, MD, PhD

• A Systematic Approach to Interpreting Medical Liver Biopsies – Meredith Pittman, MD

• Update on Hepatic Vascular Diseases – Kiyoko Oshima, MD

• Practical Topics in Tumor Immunology: What are Immune Check Point Inhibitors and How Do They Impact Anatomic Pathology? – Robert Anders, MD, PhD

• Spindle Cell Lesions of the GI Tract: Just Like Real Estate, It’s All About Location – Elizabeth Montgomery, MD

• Burning Issues in Barrett Esophagus – Elizabeth Montgomery, MD

• Gastritis: A Pattern-Based Medicine – Lysandra Voltaggio, MD

• A Rock-Solid Approach to Solid Tumors of the Pancreas – Elizabeth Thompson, MD, PhD

Learning Objectives

At the conclusion of this activity, the participant will be able to:

• Describe the development and use of checkpoint inhibitor (PD-1/L1) immune cancer therapy in laboratory medicine
• Discuss some immunolabeling pitfalls in interpreting biopsies of spindle cell neoplasms of the gastrointestinal tract
• Outline the American College of Gastroenterology guidelines for management of Barrett esophagus
• Describe findings in neoplastic lesions and dysplasia
• Recognize and differentiate the patterns of reflux, eosinophilic, lymphocytic, sloughing, infectious and pill-induced esophagitis
• Recognize that an algorithmic approach can simplify the practice of pancreatic pathology
• Recognize the role of expanded genetic testing for patients with colorectal cancer
• Identify common hepatic vascular diseases related to obstruction/obliteration of large and small hepatic veins, obliteration of small portal veins, and entities associated with non-cirrhotic portal hypertension
• Differentiate between common patterns of liver injury

Intended Audience

This activity is intended for community pathologists, gastrointestinal specialists, hepatologists and gastrointestinal, and hepatology fellows and residents.